HEY FDA, Since You’re NOT A DOCTOR, You Should Know This: Ivermectin exerts anti-cancer effects through at least 15 different pathways proven in the medical literature, both in vitro and in vivo!
DR WILLIAM MAKIS believes that it is a reasonable hypothesis that COVID-19 mRNA Vaccine Turbo Cancer patients could benefit from High Dose Ivermectin regimens, such as 2mg/kg, daily or every two days.
DR WILLIAM MAKIS, MD:
Ivermectin exerts anti-cancer effects through at least 15 different pathways proven in the medical literature, both in vitro and in vivo!
(You get a nice summary of these 15 pathways from the 2021 paper by Mingyang Tang et al.)
First, let’s quickly summarize the anti-cancer mechanisms (a quick summary can be found in 2022 paper by Loftalizadeh et al):
Ivermectin induces tumor cell death: apoptosis, autophagy, pyroptosis
Ivermectin inhibits tumor initiation and tumor progression (via WNT inhibition, YAP1 inhibition)
Ivermectin inhibits tumor growth and proliferation (via Akt/mTOR inhibition, MAPK inhibition)
Ivermectin stops cancer cell migration, invasion and metastasis (via PAK1 inhibition - seen in 70% of all cancers, EMT inhibition, RNA Helicase inhibition)
Ivermectin causes cancer cell mitochondrial dysfunction (inhibits mitochondrial biogenesis, increases reactive oxygen species selectively only in cancer cells)
Ivermectin regulates tumor microenvironment (to inhibit tumor growth and progression, via P2X7 path, ICD - mediates immunogenic cell death)
Ivermectin inhibits cancer stem cells (which are responsible for tumor initiation, progression and recurrence)
Ivermectin inhibits tumor angiogenesis (tumor blood vessel creation)
Ivermectin has anti-mitotic activity (interacts with mammalian tubulin)
Ivermectin is an epigenetic regulator of cancer to inhibit cancer progression (alters gene expression to inhibit cancer progression, SIN3A, EMT)
Ivermectin can overcome tumor multidrug resistance
What cancers can Ivermectin treat?
The top 5 COVID-19 mRNA Vaccine Induced Turbo Cancers are: lymphomas, brain cancers, breast cancers, colon cancers and lung cancers (signals also seen in leukemias, hepatobiliary cancers, testicular cancers, sarcomas and melanomas)
Ivermectin has been shown to kill these cancer cells (in vitro or in vivo):
breast cancer, especially triple negative breast cancer which is often seen in COVID-19 mRNA Vaccinated women and has the worst prognosis.
glioblastoma and gliomas (glioblastomas are often seen in COVID-19 mRNA Vaccinated individuals)
leukemias, both AML and CML (these are the most aggressive and quickly lethal mRNA Turbo Cancers)
colorectal cancer (Stage 4 Colon cancers common in COVID-19 mRNA vaccinated)
hepatobiliary cancers: hepatocecullar carcinoma, cholangiocarcinoma, pancreatic cancer (major signal with COVID-19 mRNA Vaccines)
lung cancer (Stage 4 lung cancers in COVID-19 mRNA Vaccinated)
melanoma (definite signal in COVID-19 mRNA vaccinated)
renal cell cancer (possible signal with mRNA Turbo Cancers) and urothelial carcinoma
ovarian cancer (possible signal with mRNA Turbo Cancers)
prostate cancer (possible signal with mRNA Turbo Cancers)
There is almost no literature on Ivermectin and lymphomas which are probably the most common COVID-19 mRNA vaccine turbo cancers - this must be investigated.
What dose of Ivermectin to treat COVID-19 mRNA Vaccine Turbo Cancer?
Guzzo et al published a paper in 2022 on the “Safety, tolerability, and pharmacokinetics of escalating high doses of Ivermectin in healthy adult subjects”
The highest dose tested to be safe with no side effects, was 2 mg/kg.
Max concentration in plasma is 4 hours after oral intake
Half life is 18 hours
Dr.David E. Scheim PhD, Blacksburg VA also wrote an interesting article on Ivermectin Safety in Sep.7, 2021 (Source)
Several studies have shown that Ivermectin’s anti-cancer effects are DOSE-DEPENDENT (higher dose = better response)
Warning: not to be taken as medical advice - hypothetical situation: if I was faced with a COVID-19 Vaccine Induced Turbo Cancer or an advanced stage cancer, I would be looking at an Ivermectin dose of 2mg/kg orally, daily or every two days.
Dr. Justus Hope MD published an article on Aug.29, 2023 that discusses anecdotal cases of Stage 4 Colon cancer, Stage 4 Ovarian Cancer responding to Ivermectinwith dramatic drop in Tumor markers.
High-dose Ivermectin shrinks cancer metastases
Also mentioned is a “High Dose Ivermectin” regimen of 2mg/kg per day for a doctor with Stage 4 Gallbladder cancer, taken for over a year, with visual side effects for a few days initially which resolved.
Also described is a case of enlarged Prostate suspicious for cancer, and a 5 week Ivermectin45mg/day regimen that dropped PSA from 89.1 to 10.9 with resolution of nocturnal urinary frequency. For a 100kg man, that is a dose of 0.45mg/kg, significantly lower than the 2 mg/kg safe dose published by Guzzo et al.
The article describes a cancer patient with a neck tumor and lung metastases on a High Dose Ivermectin regimen of 2.45mg/kg daily.
I believe that it is a reasonable hypothesis that COVID-19 mRNA Vaccine Turbo Cancer patients could benefit from High Dose Ivermectin regimens, such as 2mg/kg and we urgently need more research to be done in this area.
(mRNA Vaccine Induced Turbo Cancers such as leukemias, glioblastomas, breast cancers (including triple negative), colon cancers, hepatobiliary cancers, lung cancers, melanomas, renal cell cancers, ovarian cancers, prostate cancers - as there is already evidence in the literature)
Based on the above information, if one were afflicted with “vaccine” induced turbo cancer, then one could greatly increase the Ivermectindose (i.e. 2mg/kg) in the below treatment, as well as double or even quadruple the Fenbendazole dose with no toxicity whatsoever:
New & Improved Joe Tippens Protocol
Tocotrienol and Tocopherol forms (all 8) of Vitamin E (400-800mg per day, 7 days a week). A product called Gamma E by Life Extension or Perfect E are both great.
Bio-Available Curcumin (600mg per day, 2 pills per day 7 days a week). A product called Theracurmin HP by Integrative Therapeutics is bioavailable.
CBD oil (1-2 droppers full [equal to 25mg per day] under the tongue, 7 days a week) https://www.soothingsolutionscbd.com/product/3500mg-full-spectrum-cbd-tincture/ (Please use code 2SGPET for 10% off on this full spectrum CBD oil.)
Fenbendazole (300mg, 7 days a week).
Ivermectin (24mg, 7 days a week).
Removing sugars and carbohydrates from one’s diet is crucial during this protocol.
SOURCE:
How long a length of time might one take if one is not under care of doctor? Many Indians take a course once a year as a preventative for esxample but for how may days or weeks - it is never indicated. What is the length of a course of Ivermectin for cancer?